Our research activity focuses on colorectal carcinomas. We genetically
classified colorectal carcinomas as chromosomal instability
and microsatellite instability, and searching for the target
genes and their roles in cancer progression in each genetic
We carry out mutation analyses of the candidate target genes,
and systematic search of the target genes by using bioinformatics.
We are also searching differentially expressed genes by using
oligonucleotide array and proteomics study, and determining
their biological significance in relation to the biological
behavior of colorectal cancer.
You can find and analyze our clinical, pathological and molecular
genetics data on www.colonca.org. We hope for active collaborative
analysis and research with any researchers in this field.
We also carry out molecular genetic studies on gastrointestinal
stromal tumors, gastric carcinomas and hepatocellular carcinomas
under the same purpose of identifying new molecular markers
and establishing molecular classifications related to the
biological behavior of tumors.