ΆΒ Name : Hoguen Kim, M.D. & Ph.D.
 ΆΒ Present Position : Avison Distinguished Professor
 ΆΒ Address : Department of Pathology, Yonsei University College of Medicine 134 Sinchon-dong, Seodaemun-gu Seoul 120-752, Republic of Korea
 ΆΒ TEL : 82-2-2228-1761, FAX: 82-2-363-5263
 ΆΒ Homepage : www.molpathol.org

  1974-1980: Medical student, Yonsei University College of Medicine
1980-1988: Post-graduate student of Ph. D. course in Department of Pathology Yonsei University, College of Medicine
1980: M.D., Yonsei University, College of Medicine
1988: Ph. D., Yonsei University, College of Medicine
  1980-1984: Clinical trainee, Department of Pathology, Yonsei University, College of Medicine
1992-1994: Post-doctoral fellow, Division of Gasrointestinal Pathology, Department of Pathology, Johns Hopkins Medical University at Baltimore, U.S.A.
  1984-1987: Head, Department of Surgical Pathology, Tae-Jon Army Hospital
1987-1990: Instructor, Department of Pathology, Yonsei University, College of Medicine
1990-1995: Assistant Professor, Department of Pathology, Yonsei University, College of Medicine
1996-2000: Associate Professor, Department of Pathology, Yonsei University College of Medicine
2001-present: Professor of Pathology
 

Korean Cancer Association
Pathology Society of Korea
International Academy of Pathology
American Association for Cancer Research

 

Molecular genetics of gastrointestinal cancer
Genetic instability and carcinogenesis
Gastrointestinal pathology

 

1. Hyunki Kim, Suk Woo Nam, Hwanseok Rhee, Long Shan Li, Hyun Ju Kang, Kwi Hye Koh, Nam Kyu Kim, Jaehwi Song, Edison Tak-Bun Liu and Hoguen Kim. Different gene expression profiles between microsatellite instability-high and microsatellite stable colorectal carcinomas. Oncogene 23: 6218-6225, 2004

2. Long Shan Li, Nam-Gyun Kim, Se Hoon Kim, Chanil park, Hyunki Kim, Hyun Ju Kang, Kwi Hye Koh, Soo Nyung Kim, Won Ho Kim, Nam Kyu Kim, Hoguen Kim. Chromosomal imbalances in the colorectal carcinomas with microsatellite instability. Am J Pathol 163: 1429-1436, 2003

3. Nam-Gyun Kim, Hwanseok Rhee, Long Shan Li, Hyunki Kim, Jin-Sung Lee, Joo-Hang Kim, Nam Kyu Kim, Hoguen Kim. Identification of MARCKS, FLJ11383 and TAF1B as Putative Novel Target Genes in Colorectal Carcinomas with Microsatellite Instability. Oncogene 21:5081-5087, 2002

4. Nam-Gyun Kim, Yon Rak Choi, Myung Jin Baek, Haeyoun Kang, Nam Kyu Kim, Jin Sik Min, Hoguen Kim. Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability. Cancer Res 61:36-38, 2001

5. Yun Hee Kim, Nam-Gyun Kim, Jong Gun Lim, Chanil Park, Hoguen Kim. Chromosomal alterations in paired gastric adenomas and carcinomas. Am J Pathol 158:655-662, 2001

6. MicroRNA-494 Downregulates KIT and Inhibits Gastrointestinal Stromal Tumor Cell Proliferation. Clin Cancer Res 17(24); 7584-94. 2011

7. Selective Translational Repression of Truncated Proteins from Frameshift mutation-Derived mRNAs in Tumors. PLoS Biol. 24:5(5):e109 1098-1109, 2007

8. Identification and Selective Degradation of Neopeptide-Containing Truncated Mutant Proteins in the Tumors with High Microsatellite Instability. Clin Cancer Res 19(13); 3369-3382. 2013

9. Protein Kinase C-d Mediated Recycling of Active KIT in Colon Cancer. Clin Cancer Res (Epub ahead of print) 2013

10. Characterization of gene expression and activated signaling pathways in solid-pseudopapillary neoplasm of pancreas. Modern Pathology, in press(2013).